SCHEMBL16889223

SCHEMBL16889223

c1cc2c3c(c1)Oc1c(ccc4ccccc14)B3c1ccc3ccccc3c1O2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 5/20 0.37
CYP2A6 P11509 3/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPRT1 P00492 1/20 0.34
CYP1A2 P05177 5/20 0.33
HPGD P15428 3/20 0.33
KDM4E B2RXH2 3/20 0.33
CYP2C19 P33261 2/20 0.33
GLA P06280 1/20 0.33
CYP2C9 P11712 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
THRB P10828 1/20 0.32
AHR P35869 2/20 0.32
CYP3A4 P08684 1/20 0.31
KEAP1 Q14145 1/20 0.31
HCRTR1 O43613 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16889515 0.94 ALDH1A1 (0.32) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL16890683 0.87 HPRT1 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL16891157 0.86 AHR (0.33) CYP2A6CYP1A2CYP1B1AHR
SCHEMBL16891136 0.85 AHR (0.33) CYP2A6CYP1A2CYP1B1AHRMAPK1
SCHEMBL16890636 0.85 KDM4E (0.36) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL16891144 0.84 CYP1B1 (0.33) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL20375803 0.82
SCHEMBL23432318 0.82 ESR1 (0.30)
SCHEMBL16889604 0.82 KDM4E (0.35) ALDH1A1HSD17B10TSHRTDP1CYP1A2
SCHEMBL16889521 0.82 ALDH1A1 (0.34) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-11708383-B2 Organic borane complex, composition containing organic borane, and organic electroluminescent element Konica Minolta, Inc. (JP) 2023-07-25 US disclosed
US-11708383-B2 Organic borane complex, composition containing organic borane, and organic electroluminescent element Konica Minolta, Inc. (JP) 2023-07-25 US disclosed
US-11647666-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-09 US disclosed
US-11647666-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-09 US disclosed
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-02-08 US disclosed
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-02-08 US disclosed
EP-3109253-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2016-12-28 EP disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
WO-2015102118-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2015-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR ALDH1A1 2290/4885HSD17B10 1498/4885CYP2A6 303/4885
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 ALDH1A1 2119/4885HSD17B10 4513/4885CYP2A6 848/4885
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 ALDH1A1 3052/4885HSD17B10 3889/4885CYP2A6 2018/4885
US-11708383-B2 Organic borane complex, composition containing organic borane, and organic electroluminescent element ORC3, OR10J3, OSBP ALDH1A1 3470/4885HSD17B10 2966/4885CYP2A6 3265/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 ALDH1A1 3052/4885HSD17B10 3889/4885CYP2A6 2018/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR ALDH1A1 2965/4885HSD17B10 4581/4885CYP2A6 701/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 ALDH1A1 3052/4885HSD17B10 3889/4885CYP2A6 2018/4885
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION C9, TYR, CCNA1 ALDH1A1 990/4885HSD17B10 3137/4885CYP2A6 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.