SCHEMBL16890260

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17008149	0.79	FFAR4 (0.39)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL10029994	0.76	ALDH1A1 (0.47)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL12258331	0.76	KDM4E (0.56)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL27109841	0.75	KDM4E (0.48)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL23491244	0.75	NR1H2 (0.41)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL16889924	0.74	KDM4E (0.57)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL21348640	0.74	KDM4E (0.47)	KDM4EL3MBTL1ATMALDH1A1HTR1A
	SCHEMBL28477376	0.73	KDM4E (0.61)	KDM4EL3MBTL1ATMLTA4HTSHR
	SCHEMBL12795612	0.72	GSTP1 (0.47)	KDM4EL3MBTL1ATMALDH1A1POLB
	SCHEMBL3904085	0.72	KDM4E (0.65)	KDM4EL3MBTL1ATMLTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.