SCHEMBL28477376

SCHEMBL28477376

c1ccc(Oc2cccc(-n3c4ccccc4c4ccccc43)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.61
ATM Q13315 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
MAOB P27338 1/20 0.46
LTA4H P09960 1/20 0.44
TSHR P16473 1/20 0.44
PPARG P37231 4/20 0.43
NTRK1 P04629 2/20 0.42
IGF1R P08069 2/20 0.42
FGFR1 P11362 2/20 0.42
NTRK2 Q16620 2/20 0.42
AKR1C3 P42330 1/20 0.42
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
PPARA Q07869 1/20 0.40
REN P00797 3/20 0.40
SCN9A Q15858 1/20 0.40
NTRK3 Q16288 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16890333 0.94 KDM4E (0.57) KDM4EATML3MBTL1MAOBPPARG
SCHEMBL10331581 0.89 KDM4E (0.53) KDM4EATML3MBTL1MAOBPPARG
SCHEMBL28475204 0.88 L3MBTL1 (0.60) KDM4EATML3MBTL1MAOBLTA4H
SCHEMBL18903844 0.88 L3MBTL1 (0.47) KDM4EATML3MBTL1MAOBPPARG
SCHEMBL16890212 0.87 KDM4E (0.53) KDM4EATML3MBTL1MAOBPPARG
SCHEMBL16889924 0.87 KDM4E (0.57) KDM4EATML3MBTL1MAOBLTA4H
SCHEMBL16889994 0.86 KDM4E (0.58) KDM4EATML3MBTL1MAOBPPARG
SCHEMBL16890387 0.85 KDM4E (0.52) KDM4EATML3MBTL1MAOBPPARG
SCHEMBL22894331 0.85 KDM4E (0.47) KDM4EATML3MBTL1PPARGNTRK1
SCHEMBL31497265 0.85 KDM4E (0.47) KDM4EATML3MBTL1PPARGNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662314-B Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-10-26 CN disclosed
CN-106905367-B Electron transport material or electron injection material, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-17 CN disclosed
CN-111909189-A Polycyclic aromatic compound, multimer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-10 CN disclosed
CN-111892615-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-06 CN disclosed
CN-105431439-B Polycyclic aromatic compound, method for producing same, material for organic device, and application thereof 学校法人关西学院 2020-09-25 CN disclosed
CN-111662314-A Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-09-15 CN disclosed