Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16890812 | 0.96 | ENPP3 (0.37) | CA12CA9CA1CA2ENPP3 | |
| SCHEMBL17013604 | 0.94 | CA12 (0.32) | CA12CA9MCL1CYP2C19CLK4 | |
| SCHEMBL16890816 | 0.92 | HTR7 (0.38) | CA12CA9ENPP3ENPP1MCL1 | |
| SCHEMBL16891089 | 0.92 | NPC1 (0.34) | ENPP3ENPP1TSHRALDH1A1KDM4E | |
| SCHEMBL16891090 | 0.90 | KDM4E (0.33) | CYP2C19CLK4CYP1A2CYP2D6TSHR | |
| SCHEMBL17013600 | 0.89 | NPC1 (0.33) | ENPP3ENPP1MCL1TSHRALDH1A1 | |
| SCHEMBL17013596 | 0.89 | NPC1 (0.33) | ENPP3ENPP1MCL1TSHRALDH1A1 | |
| SCHEMBL17013598 | 0.89 | NPC1 (0.33) | ENPP3ENPP1MCL1TSHRALDH1A1 | |
| SCHEMBL17013603 | 0.89 | NPC1 (0.33) | ENPP3ENPP1MCL1TSHRALDH1A1 | |
| SCHEMBL16890814 | 0.88 | HTR7 (0.35) | CA12CA9ENPP3ENPP1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058635-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20230059210-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2020109269-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| US-20200144514-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-05-07 | — | — | US | disclosed |
| US-20200144515-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-05-07 | — | — | US | disclosed |
| US-20200144513-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-05-07 | — | — | US | disclosed |
| US-10374166-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2019-08-06 | — | — | US | disclosed |
| EP-3345911-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL | Kwansei Gakuin Educational Foundation (JP) | 2018-07-11 | — | — | EP | disclosed |
| US-20150236274-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2015-08-20 | — | — | US | disclosed |
| US-20150236274-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2015-08-20 | — | — | US | disclosed |
| WO-2015102118-A1 | POLYCYCLIC AROMATIC COMPOUND | 学校法人関西学院 | 2015-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150236274-A1 | POLYCYCLIC AROMATIC COMPOUND | PAH, ALK, AOC2 | CA12 696/4885CA9 512/4885CA1 2201/4885 |
| US-20200144514-A1 | POLYCYCLIC AROMATIC COMPOUND | PAH, ALK, AOC2 | CA12 696/4885CA9 512/4885CA1 2201/4885 |
| US-20200144513-A1 | POLYCYCLIC AROMATIC COMPOUND | PAH, ALK, AOC2 | CA12 696/4885CA9 512/4885CA1 2201/4885 |
| US-20200144515-A1 | POLYCYCLIC AROMATIC COMPOUND | PAH, ALK, AOC2 | CA12 696/4885CA9 512/4885CA1 2201/4885 |
| US-10374166-B2 | Polycyclic aromatic compound | PAH, ALK, AOC2 | CA12 696/4885CA9 512/4885CA1 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.