Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689099 | 0.78 | MAPK8 (0.40) | HTTCNR1MAPK8MAPK10LMNA | |
| SCHEMBL5263268 | 0.77 | HTT (0.41) | HTTCNR1MAPK8MAPK10LMNA | |
| SCHEMBL16516909 | 0.73 | HCAR2 (0.36) | CCNT1CCNA2CDK2CDK9NTRK1 | |
| SCHEMBL1689336 | 0.71 | CCNA2 (0.42) | CCNT1CCNA2CDK2CDK9NTRK1 | |
| SCHEMBL2954127 | 0.70 | HTT (0.59) | HTTCNR1MAPK8MAPK10LMNA | |
| SCHEMBL5565066 | 0.68 | CNR1 (0.47) | HTTCNR1CNR2 | |
| SCHEMBL1689037 | 0.68 | CYP1A2 (0.36) | HTTCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL5263270 | 0.67 | WNT1 (0.47) | HTTMAPK8MAPK10CLK2CLK3 | |
| SCHEMBL5308763 | 0.65 | P2RX7 (0.54) | HTTCNR1CNR2 | |
| SCHEMBL5616254 | 0.65 | GABRG2 (0.38) | LMNANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |