Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688887 | 0.89 | MAPT (0.36) | MEN1KMT2AGRM1DPP4MAPT | |
| SCHEMBL1688907 | 0.86 | GRM1 (0.44) | MEN1KMT2AGRM1MAPTNPC1 | |
| SCHEMBL1753151 | 0.78 | MAPT (0.56) | GRM1DPP4MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1688913 | 0.77 | MEN1 (0.51) | MEN1KMT2AGRM1MAPTIDO1 | |
| SCHEMBL5611981 | 0.76 | ADORA3 (0.41) | MEN1KMT2AALDH1A1POLBPDE10A | |
| SCHEMBL5611595 | 0.75 | GRM1 (0.41) | MEN1KMT2AGRM1MAPTALDH1A1 | |
| SCHEMBL1688936 | 0.75 | MEN1 (0.47) | MEN1KMT2AGRM1MAPTALDH1A1 | |
| SCHEMBL5611923 | 0.74 | MEN1 (0.38) | MEN1KMT2AGRM1MAPTIDO1 | |
| SCHEMBL1688977 | 0.73 | GRM1 (0.39) | MEN1KMT2AGRM1MAPTALDH1A1 | |
| SCHEMBL5611700 | 0.73 | MEN1 (0.52) | MEN1KMT2AGRM1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |