Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688907 | 0.87 | GRM1 (0.44) | MEN1KMT2AKDM4ERXFP1GRM1 | |
| SCHEMBL1688913 | 0.86 | MEN1 (0.51) | MEN1KMT2AKDM4ESMN1; SMN2GRM1 | |
| SCHEMBL5611595 | 0.84 | GRM1 (0.41) | MEN1KMT2AALDH1A1KDM4EGRM1 | |
| SCHEMBL1689317 | 0.84 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5611700 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1688977 | 0.82 | GRM1 (0.39) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1689078 | 0.81 | MAPT (0.61) | MEN1KMT2AALDH1A1LMNARXFP1 | |
| SCHEMBL5611521 | 0.81 | MAPT (0.61) | MEN1KMT2AALDH1A1LMNARXFP1 | |
| SCHEMBL1688877 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1KDM4EGRM1 | |
| SCHEMBL1688905 | 0.81 | MAPT (0.52) | MEN1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |