Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688913 | 0.90 | MEN1 (0.51) | GRM1MAPTMEN1KMT2APTGS2 | |
| SCHEMBL5611981 | 0.89 | ADORA3 (0.41) | MEN1KMT2AKDM4EADORA3 | |
| SCHEMBL5611595 | 0.88 | GRM1 (0.41) | GRM1MAPTMEN1KMT2APTGS2 | |
| SCHEMBL1688936 | 0.87 | MEN1 (0.47) | GRM1MAPTMEN1KMT2APTGS2 | |
| SCHEMBL1689119 | 0.86 | MEN1 (0.37) | GRM1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1688977 | 0.85 | GRM1 (0.39) | GRM1MAPTMEN1KMT2APTGS2 | |
| SCHEMBL1689078 | 0.84 | MAPT (0.61) | GRM1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL5611521 | 0.84 | MAPT (0.61) | GRM1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL1688905 | 0.84 | MAPT (0.52) | GRM1MAPTMEN1KMT2APTGS2 | |
| SCHEMBL5612440 | 0.83 | POLB (0.45) | GRM1KMT2AKDM4EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | disclosed |