SCHEMBL16891329

SCHEMBL16891329

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CXCL8 P10145 9/20 0.57
▸ C5AR1 P21730 2/20 0.56
▸ DPP3 Q9NY33 5/20 0.56
▸ REN P00797 1/20 0.55
▸ SLC6A2 P23975 1/20 0.55
▸ OPRM1 P35372 2/20 0.54
▸ OPRD1 P41143 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953538 0.91 DPP3 (0.62) C5AR1DPP3RENSLC6A2OPRM1
SCHEMBL19787869 0.87 DPP3 (0.69) C5AR1DPP3RENSLC6A2OPRM1
SCHEMBL30949447 0.87 CXCL8 (0.63) CXCL8SLC6A2
SCHEMBL29733647 0.87 C5AR1 (0.63) CXCL8C5AR1
SCHEMBL30512506 0.86 CXCL8 (0.61) CXCL8DPP3OPRM1
SCHEMBL29575470 0.86 DPP3 (0.61) C5AR1DPP3SLC6A2OPRM1OPRD1
SCHEMBL31402672 0.86 KISS1R (0.63) DPP3RENSLC6A2OPRM1
SCHEMBL30311066 0.86 CXCL8 (0.63) CXCL8DPP3OPRM1
SCHEMBL31332301 0.85 CXCL8 (0.59) CXCL8DPP3
SCHEMBL31247508 0.85 CXCL8 (0.55) CXCL8DPP3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230058316-A1 PEGYLATED IGE-DEPENDENT HISTAMINE-RELEASING FACTOR (HRF)-BINDING PEPTIDE AND USE THEREOF EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2023-02-23 — — US disclosed
WO-2015102418-A2 PEPTIDOMIMETIC COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATING ALLERGIC DISORDERS INCLUDING SAME 이화여자대학교 산학협력단 2015-07-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230058316-A1 PEGYLATED IGE-DEPENDENT HISTAMINE-RELEASING FACTOR (HRF)-BINDING PEPTIDE AND USE THEREOF HDGF, HRH3, HRH4 CXCL8 548/4885C5AR1 40/4885DPP3 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback