Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 7/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16891348 | 0.87 | DUT (0.46) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL21325251 | 0.85 | DUT (0.45) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL15864648 | 0.84 | DUT (0.39) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL1409593 | 0.82 | DUT (0.45) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL20347946 | 0.82 | DUT (0.46) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL21315522 | 0.81 | DUT (0.50) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL20188353 | 0.81 | DUT (0.50) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL20206933 | 0.80 | DUT (0.50) | DUTHTR2CHTR2BHTR2AIDO1 | |
| SCHEMBL20204783 | 0.80 | DUT (0.53) | DUTIDO1TDO2RIPK1GRM2 | |
| SCHEMBL22414494 | 0.79 | DUT (0.45) | DUTHTR2CHTR2BHTR2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |