Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333677 | 0.83 | HSD17B10 (0.38) | PARP1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL7332315 | 0.78 | NISCH (0.38) | APOBEC3GALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL16886019 | 0.78 | NISCH (0.38) | APOBEC3GALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL7332320 | 0.78 | NISCH (0.38) | APOBEC3GALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL18820353 | 0.77 | NISCH (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11183722 | 0.75 | APOBEC3A (0.41) | APOBEC3ACTDSP1APOBEC3GNQO1ADRA2A | |
| SCHEMBL11737053 | 0.75 | MEN1 (0.40) | NQO1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18819704 | 0.75 | NISCH (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7328246 | 0.74 | ALDH1A1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7328244 | 0.74 | ALDH1A1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611276-B2 | Imidazo bicyclic iminium compounds as antitumor agents | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150191489-A1 | IMIDAZO BICYCLIC IMMINIUM COMPOUNDS AS ANTITUMOR AGENTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191489-A1 | IMIDAZO BICYCLIC IMMINIUM COMPOUNDS AS ANTITUMOR AGENTS | GLI1, SHH, SMO | APOBEC3A 3643/4885CTDSP1 2155/4885APOBEC3G 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.