Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892220 | 0.90 | SCN9A (0.55) | KDM4EALDH1A1SCN9AFPR2MAOB | |
| SCHEMBL16892177 | 0.87 | MAOB (0.60) | SCN9AMAOBMAOA | |
| SCHEMBL16892175 | 0.87 | MAOB (0.60) | SCN9AMAOBMAOA | |
| SCHEMBL16892179 | 0.84 | MAOB (0.44) | KDM4EALDH1A1SCN9AMAOBMAOA | |
| SCHEMBL8804044 | 0.84 | ALDH1A1 (0.59) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8803794 | 0.82 | MEN1 (0.59) | KDM4EALDH1A1 | |
| SCHEMBL16892163 | 0.81 | MAOB (0.57) | SCN9AMAOBMAOA | |
| SCHEMBL8803242 | 0.77 | MAOB (0.64) | KDM4EALDH1A1SCN9AMAOBMAOA | |
| SCHEMBL16892155 | 0.77 | MAOB (0.52) | SCN9AMAOBMAOA | |
| SCHEMBL16892164 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1SCN9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101294-A1 | COMPOUNDS WITH ANALGESIC ACTIVITY AND MEDICAL USE THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 | 2015-07-09 | — | — | WO | disclosed |