Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.52 |
| ▸ | MAOA | P21397 | 7/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892177 | 0.90 | MAOB (0.60) | MAOBMAOASCN9ANPC1RAB9A | |
| SCHEMBL16892175 | 0.90 | MAOB (0.60) | MAOBMAOASCN9ANPC1RAB9A | |
| SCHEMBL16892201 | 0.86 | MAOB (0.52) | MAOBMAOASCN9ANPC1RAB9A | |
| SCHEMBL16892163 | 0.80 | MAOB (0.57) | MAOBMAOASCN9ANPC1RAB9A | |
| SCHEMBL16892162 | 0.80 | SPHK2 (0.58) | MAOBMAOANPC1RAB9A | |
| SCHEMBL964720 | 0.78 | MAOB (0.66) | MAOBMAOASCN9A | |
| SCHEMBL16892156 | 0.77 | KDM4E (0.51) | MAOBMAOASCN9A | |
| SCHEMBL964393 | 0.76 | MAOB (0.80) | MAOBMAOASCN9A | |
| SCHEMBL966825 | 0.74 | SCN9A (0.62) | MAOBMAOASCN9A | |
| SCHEMBL6395296 | 0.74 | MEN1 (0.56) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101294-A1 | COMPOUNDS WITH ANALGESIC ACTIVITY AND MEDICAL USE THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 | 2015-07-09 | — | — | WO | disclosed |