Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A2 | O94788 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611678 | 0.90 | MAPT (0.52) | ALDH1A1MAPTRXFP1TP53MEN1 | |
| SCHEMBL1688889 | 0.89 | MAPT (0.49) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL5611869 | 0.89 | MAPT (0.49) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL1688905 | 0.87 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL1688903 | 0.85 | MAPT (0.46) | ALDH1A2ALDH1A1ALDH1A3MAPTRXFP1 | |
| SCHEMBL1688877 | 0.85 | ALDH1A1 (0.39) | ALDH1A2ALDH1A1ALDH1A3MAPTMEN1 | |
| SCHEMBL1688979 | 0.84 | GRM1 (0.40) | ALDH1A2ALDH1A1ALDH1A3MAPTPKM | |
| SCHEMBL5611971 | 0.84 | GRM1 (0.41) | ALDH1A2ALDH1A1ALDH1A3MAPTPKM | |
| SCHEMBL1688917 | 0.84 | ALDH1A1 (0.41) | ALDH1A2ALDH1A1ALDH1A3MAPTRXFP1 | |
| SCHEMBL1689010 | 0.84 | MAPT (0.45) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |