Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537494 | 0.85 | KMT2A (0.38) | RAPGEF4 | |
| SCHEMBL909187 | 0.85 | KMT2A (0.38) | RAPGEF4 | |
| SCHEMBL909752 | 0.85 | KMT2A (0.38) | RAPGEF4 | |
| SCHEMBL5153705 | 0.80 | ALDH1A1 (0.33) | RAPGEF4 | |
| SCHEMBL27206070 | 0.80 | KDM4E (0.39) | — | |
| SCHEMBL3812470 | 0.79 | MEN1 (0.34) | RAPGEF4 | |
| SCHEMBL3809686 | 0.79 | MEN1 (0.34) | RAPGEF4 | |
| SCHEMBL20184269 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL32681961 | 0.78 | SLC6A2 (0.37) | — | |
| SCHEMBL2484468 | 0.76 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240491-B1 | TETRAHYDROFURO(2,3-b)PYRROL-3-ONE DERIVATIVES AS INHIBITORS OF CYSTEINE PROTEINASES | AMURA THERAPEUTICS LTD (GB) | 2015-07-15 | — | — | EP | disclosed |