Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067927 | 0.88 | FGFR1 (0.45) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7971117 | 0.81 | MAOA (0.58) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL11688264 | 0.77 | KMT2A (0.54) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL15669790 | 0.77 | MAOA (0.46) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL16894421 | 0.75 | MAOA (0.44) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL16894501 | 0.74 | MAOA (0.59) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL28962389 | 0.73 | MAOA (0.41) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL30040785 | 0.73 | MAOA (0.41) | MAOAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL22325684 | 0.73 | CA12 (0.59) | MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL12170332 | 0.71 | SRD5A2 (0.68) | MAOAMEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861570-B1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | UNIV RUTGERS (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9592221-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-15 | — | — | US | disclosed |
| US-9315495-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | PROVID PHARMACEUTICALS INC. | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | POLRMT, POLR1C, FBL | MAOA 682/4885MEN1 3377/4885KMT2A 3554/4885 |
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | FBL, POLRMT, POLR1C | MAOA 517/4885MEN1 3495/4885KMT2A 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.