Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.72 |
| ▸ | GABRD | O14764 | 3/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.72 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.72 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.72 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.72 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.72 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.72 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.72 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.72 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.72 |
| ▸ | GABRE | P78334 | 3/20 | 0.72 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.72 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.72 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.72 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.69 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.69 |
| ▸ | TNKS | O95271 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538912 | 0.89 | GABRP (0.84) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16894631 | 0.86 | GABRP (0.81) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10024074 | 0.85 | CSNK2A2 (0.82) | CSNK2A2CSNK2BCSNK2A1TNKSPARP1 | |
| SCHEMBL13855909 | 0.84 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14433139 | 0.84 | GABRP (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4990126 | 0.84 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4985411 | 0.83 | ALDH1A1 (0.76) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10144247 | 0.83 | GABRP (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7568626 | 0.82 | TNKS (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6656060 | 0.81 | GABRP (0.82) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | disclosed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | GABRP 64/4885GABRD 142/4885GABRA1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.