Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 7/20 | 1.00 |
| ▸ | PARP1 | P09874 | 4/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 1.00 |
| ▸ | CSNK2B | P67870 | 1/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 1.00 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.71 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.71 |
| ▸ | GABRP | O00591 | 5/20 | 0.69 |
| ▸ | GABRD | O14764 | 5/20 | 0.69 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.69 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.69 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.69 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.69 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.69 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.69 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.69 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538912 | 0.87 | GABRP (0.84) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL5064064 | 0.86 | GABRP (0.80) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL6656060 | 0.84 | GABRP (0.82) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL14433139 | 0.82 | GABRP (0.72) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL13855909 | 0.82 | GABRP (0.75) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL16894657 | 0.82 | GABRP (0.72) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL4990126 | 0.82 | GABRP (1.00) | TNKSPARP1TNKS2PARP2CSNK2A2 | |
| SCHEMBL23070093 | 0.81 | TNKS (0.93) | TNKSPARP1TNKS2PARP2PLA2G2A | |
| Flavone SCHEMBL18879 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2PARP2PLA2G2A | |
| Flavone SCHEMBL15676601 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2PARP2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236118-B1 | Selective cyclocarbonylative coupling of 2-iodophenols with terminal alkynes catalyzed by bridged bis(NHC)Pd(II)Br2 catalysts | KING FAHD UNIVERSITY OF PETROLEUM & MINERALS (SA) | 2022-02-01 | — | — | US | disclosed |
| EP-0857066-B1 | USE OF NITROFLAVONOIDS FOR THE TREATMENT OF ANXIETY | UNIV STRATHCLYDE (GB) | 2002-05-29 | — | — | EP | disclosed |
| US-6080780-A | ADMINISTERING TO THE PATIENT A NITROFLAVANOID TO TREAT THE ANXIETY | UNIVERSITY OF STRATHCLYDE (GB) | 2000-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236118-B1 | Selective cyclocarbonylative coupling of 2-iodophenols with terminal alkynes catalyzed by bridged bis(NHC)Pd(II)Br2 catalysts | BRD2, BICRA, RAD52 | TNKS 1399/4885PARP1 63/4885TNKS2 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.