⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183299 | 0.97 | TRPA1 (0.31) | — | |
| SCHEMBL166888 | 0.97 | — | — | |
| SCHEMBL8734069 | 0.97 | TRPA1 (0.31) | — | |
| SCHEMBL8579729 | 0.97 | TRPA1 (0.31) | — | |
| SCHEMBL168854 | 0.97 | TRPA1 (0.31) | — | |
| SCHEMBL165910 | 0.97 | TRPA1 (0.31) | — | |
| SCHEMBL320565 | 0.97 | TRPA1 (0.31) | — | |
| SCHEMBL183105 | 0.97 | — | — | |
| SCHEMBL165972 | 0.90 | — | — | |
| SCHEMBL820047 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191482-B1 | 1,2,3-THIADIAZOL-5YL-UREA DERIVATIVES, USE THEREOF FOR REGULATING PLANT SENESCENCE AND PREPARATIONS CONTAINING THESE DERIVATIVES | USTAV EXPERIMENTALNI BOTANIKY AV CR V V I (CZ) | 2019-03-27 | — | — | EP | claimed |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | PFIZER INC. | 2007-09-27 | — | — | US | claimed |
| EP-1678164-B1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORP (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1678146-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1678164-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1611166-A2 | BUILDING SEALANT COMPOSITION | Bridgestone Corporation (JP) | 2006-01-04 | — | — | EP | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005040133-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-05-06 | — | — | WO | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2005035527-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-21 | — | — | WO | claimed |
| WO-2004090060-A2 | BUILDING SEALANT COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2004-10-21 | — | — | WO | claimed |
| EP-4400561-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2024-07-17 | — | — | EP | disclosed |
| CN-118325625-A | Liquid-crystalline medium | 默克专利股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240216312-A1 | PPAR-AGONISTS FOR USE IN THE TREATMENT OF LIVER FAILURE | GENFIT (FR) | 2024-07-04 | — | — | US | disclosed |
| US-20240222110-A1 | PARTIAL BREAKDOWN OF PRECURSORS FOR ENHANCED ALD FILM GROWTH | ASM IP HOLDING B.V. (NL) | 2024-07-04 | — | — | US | disclosed |
| EP-0554023-A1 | Corrosion inhibitors | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| US-5183842-A | Mixture of ketoacid and amine with film-forming binder, curing | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0496555-A2 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1992-07-29 | — | — | EP | disclosed |
| US-5128396-A | Corrosion inhibiting primers on metallic substrates | CIBA-GEIGY CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0412933-A1 | Coating compositions | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |