SCHEMBL165910

SCHEMBL165910

[CH2]CCCCCCCCC=S

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320565 1.00 TRPA1 (0.31) TRPA1
SCHEMBL183299 1.00 TRPA1 (0.31) TRPA1
SCHEMBL8579729 1.00 TRPA1 (0.31) TRPA1
SCHEMBL183105 1.00
SCHEMBL168854 1.00 TRPA1 (0.31) TRPA1
SCHEMBL8734069 1.00 TRPA1 (0.31) TRPA1
SCHEMBL166888 1.00
SCHEMBL168949 0.97
SCHEMBL165972 0.87
SCHEMBL7114578 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181607-A1 THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION The University of the Regents of California (US) 2023-06-15 US disclosed
EP-4149481-A1 THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION The Regents of the University of California (US) 2023-03-22 EP disclosed
CN-115177626-A Thiosyl mucolytic agents and uses and compositions thereof 加利福尼亚大学董事会 2022-10-14 CN disclosed
CN-105228605-B Thiosyl mucolytic agents 加利福尼亚大学董事会 2022-08-12 CN disclosed
WO-2021231397-A1 THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-11-18 WO disclosed
EP-3891818-A1 SELF-ASSEMBLED MONOLAYER FOR ELECTRODE MODIFICATION AND DEVICE COMPRISING SUCH SELF-ASSEMBLED MONOLAYER Merck Patent GmbH (DE) 2021-10-13 EP disclosed
CN-108024913-B Curable composition, curable composition for dentistry, and organic-inorganic composite particle for dentistry 德山齿科株式会社 2021-08-10 CN disclosed
EP-3851109-A1 THIOSACCHARIDE MUCOLYTIC AGENTS The Regents of the University of California (US) 2021-07-21 EP disclosed
US-11021506-B2 Thiosaccharide mucolytic agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-01 US disclosed
EP-2968215-B1 THIOSACCHARIDE MUCOLYTIC AGENTS UNIV CALIFORNIA (US) 2021-05-05 EP disclosed
US-20030216412-A1 Methanocarba cycloakyl nucleoside analogues HEALTH AND HUMAN SERVICES, GOVERNMENT OF THE UNITED STATES OF AMERICA, THE, REPRESENTED BY THE SECRETARY, DEPARTMENT OF 2003-11-20 US disclosed
US-20030027785-A1 Joint lubrication with P2Y purinergic receptor agonists INSPIRE PHARMACEUTICALS, INC. 2003-02-06 US disclosed
WO-2003000056-A1 JOINT LUBRICATION WITH P2Y PURINERGIC RECEPTOR AGONISTS INSPIRE PHARMACEUTICALS, INC. (US) 2003-01-03 WO disclosed
WO-2002086000-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-1252160-A1 METHANOCARBA CYCLOALKYL NUCLEOSIDE ANALOGUES THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2002-10-30 EP disclosed
WO-2001051490-A1 METHANOCARBA CYCLOALKYL NUCLEOSIDE ANALOGUES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-07-19 WO disclosed
EP-0412933-B1 Coating compositions CIBA GEIGY AG (CH) 1994-09-14 EP disclosed
US-5183842-A Mixture of ketoacid and amine with film-forming binder, curing CIBA-GEIGY CORPORATION (US) 1993-02-02 US disclosed
US-5128396-A Corrosion inhibiting primers on metallic substrates CIBA-GEIGY CORPORATION (US) 1992-07-07 US disclosed
EP-0412933-A1 Coating compositions CIBA-GEIGY AG (CH) 1991-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216412-A1 Methanocarba cycloakyl nucleoside analogues P2RY1, ADORA1, ADORA2A TRPA1 130/4885
US-11021506-B2 Thiosaccharide mucolytic agents MUC1, TREH, FUT6 TRPA1 1259/4885
US-20030027785-A1 Joint lubrication with P2Y purinergic receptor agonists P2RY1, P2RY2, P2RY6 TRPA1 643/4885
US-20230181607-A1 THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION TMPRSS4, ACE, ACE2 TRPA1 1525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.