SCHEMBL183299

SCHEMBL183299

[CH2]CCCCCCCCCCCCCCCCC=S

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320565 1.00 TRPA1 (0.31) TRPA1
SCHEMBL8579729 1.00 TRPA1 (0.31) TRPA1
SCHEMBL183105 1.00
SCHEMBL165910 1.00 TRPA1 (0.31) TRPA1
SCHEMBL168854 1.00 TRPA1 (0.31) TRPA1
SCHEMBL8734069 1.00 TRPA1 (0.31) TRPA1
SCHEMBL166888 1.00
SCHEMBL168949 0.97
SCHEMBL165972 0.87
SCHEMBL7114578 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794621-B1 NOVEL ORGANOSILICA COMPOUNDS UNIV GENT (BE) 2018-09-26 EP disclosed
EP-3066147-A2 CONJUGATED POLYMERS Merck Patent GmbH (DE) 2016-09-14 EP disclosed
US-9181282-B2 Organosilica compounds UNIVERSITEIT GENT (BE) 2015-11-10 US disclosed
WO-2015067336-A2 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2015-05-14 WO disclosed
US-20150005525-A1 NOVEL ORAGNOSILICA COMPOUNDS UNIVERSITEIT GENT (BE) 2015-01-01 US disclosed
EP-2794621-A1 NOVEL ORGANOSILICA COMPOUNDS Universiteit Gent (BE) 2014-10-29 EP disclosed
WO-2013093022-A1 NOVEL ORGANOSILICA COMPOUNDS UNIVERSITEIT GENT (BE) 2013-06-27 WO disclosed
WO-2012153300-A1 BLOCK COPOLYMER-BASED SOLID ELECTROLYTES FOR DYE PHOTOVOLTAIC CELLS, AND CELLS THUS OBTAINED UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) 2012-11-15 WO disclosed
US-8252784-B2 Photoactivable nitrogen bases BASF SE (DE) 2012-08-28 US disclosed
US-8158206-B2 Method for modifying wood and wood thereby obtained TRANSFURANS CHEMICALS (BE) 2012-04-17 US disclosed
US-6277986-B1 AS PHOTOINITIATORS FOR BASE-CATALYSED REACTIONS CIBA SPECIALTY CHEMICALS CORP. 2001-08-21 US disclosed
EP-1105368-A1 PHOTOACTIVATABLE BASES CONTAINING NITROGEN Ciba SC Holding AG (CH) 2001-06-13 EP disclosed
EP-1032576-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES Ciba SC Holding AG (CH) 2000-09-06 EP disclosed
US-6087070-A AS PHOTOINITIATORS FOR BASE-CATALYZABLE REACTIONS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-07-11 US disclosed
WO-2000010964-A1 PHOTOACTIVATABLE BASES CONTAINING NITROGEN CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-02 WO disclosed
EP-0971924-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMINO KETONES Ciba SC Holding AG (CH) 2000-01-19 EP disclosed
EP-0970085-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMINO ALKENES Ciba SC Holding AG (CH) 2000-01-12 EP disclosed
WO-1998041524-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMINO ALKENES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-24 WO disclosed
WO-1998038195-A1 PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-09-03 WO disclosed
WO-1998032756-A1 SUBSTITUTED AMINOALKYLIDENAMINO TRIAZINES AS HERBICIDES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150005525-A1 NOVEL ORAGNOSILICA COMPOUNDS ORC3, ORMDL3, OR10J3 TRPA1 619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.