Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16898784 | 0.88 | MGMT (0.36) | MGMT | |
| SCHEMBL16898524 | 0.88 | MGMT (0.36) | MGMT | |
| SCHEMBL16898349 | 0.88 | MGMT (0.36) | MGMT | |
| SCHEMBL16898643 | 0.88 | MGMT (0.36) | MGMT | |
| SCHEMBL16898614 | 0.87 | MGMT (0.35) | MGMT | |
| SCHEMBL16906830 | 0.81 | USP2 (0.38) | CRBN | |
| SCHEMBL20362162 | 0.77 | MGMT (0.30) | MGMT | |
| SCHEMBL16898439 | 0.75 | MGMT (0.34) | MGMT | |
| SCHEMBL21070724 | 0.73 | CHRNB2 (0.31) | — | |
| SCHEMBL20362229 | 0.72 | LIPG (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |