Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12834807 | 0.93 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL14015624 | 0.88 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL12834865 | 0.82 | KDM4E (0.40) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL14000515 | 0.79 | NNMT (0.51) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL12834733 | 0.78 | MAPT (0.35) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13315446 | 0.75 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL8126559 | 0.71 | NNMT (0.42) | MAPTKDM4EEPHX2GRM5 | |
| SCHEMBL12364920 | 0.69 | EPHX2 (0.60) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL8515103 | 0.69 | KDM4E (0.49) | RAB9ANPC1MAPTKDM4EEPHX2 | |
| SCHEMBL217496 | 0.69 | NNMT (0.49) | MAPTKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298736-B1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INC (US) | 2015-07-15 | — | — | EP | disclosed |