Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015624 | 0.94 | RAB9A (0.42) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL12834807 | 0.88 | RAB9A (0.38) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL16901557 | 0.82 | RAB9A (0.34) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL14000515 | 0.78 | NNMT (0.51) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL12834733 | 0.75 | MAPT (0.35) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL12590041 | 0.73 | KDM4E (0.40) | KDM4EMAPTRAB9AKMT2AHCAR3 | |
| SCHEMBL12646651 | 0.73 | MEN1 (0.40) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL18518055 | 0.71 | MAPT (0.42) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL13315446 | 0.70 | NPC1 (0.54) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9605928 | 0.69 | HCAR3 (0.73) | HCAR3NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298736-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | Solulink, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |