Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1198106 | 0.98 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL7695939 | 0.85 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL62534 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL10722003 | 0.83 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8053510 | 0.83 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL4935091 | 0.83 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27368126 | 0.82 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL6854023 | 0.82 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL294341 | 0.82 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1MAPK1KMT2ASLC6A2 | |
| SCHEMBL1687346 | 0.81 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217928-A1 | HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2024-07-04 | — | — | US | disclosed |
| WO-2023006645-A1 | HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-02-02 | — | — | WO | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |
| EP-2389356-B1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | UNIV CLAUDE BERNARD LYON (FR) | 2013-10-23 | — | — | EP | disclosed |
| US-20120010161-A1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-01-12 | — | — | US | disclosed |
| US-20120010161-A1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-01-12 | — | — | US | disclosed |
| US-20120010161-A1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-01-12 | — | — | US | disclosed |
| EP-1572630-A1 | ANTIBACTERIAL AGENTS | Vernalis (Oxford) Ltd (GB) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056751-A1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2004-07-08 | — | — | WO | disclosed |
| EP-0342423-A2 | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1989-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010161-A1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | ABCB1, ABCB11, ABCC1 | ALDH1A1 2049/4885L3MBTL1 3744/4885MAPK1 2470/4885 |
| US-20240217928-A1 | HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS | NHERF1, ENPP1, ATP6AP1 | ALDH1A1 375/4885L3MBTL1 3591/4885MAPK1 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.