⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983010 | 0.73 | CRBN (0.33) | — | |
| SCHEMBL25711985 | 0.68 | ALDH1A1 (0.30) | — | |
| SCHEMBL17619680 | 0.68 | — | — | |
| SCHEMBL8664423 | 0.68 | ALDH1A1 (0.45) | — | |
| SCHEMBL14566054 | 0.67 | MGAM (0.32) | — | |
| SCHEMBL22590240 | 0.67 | LMNA (0.35) | — | |
| SCHEMBL24567199 | 0.65 | — | — | |
| SCHEMBL8514942 | 0.65 | ALDH1A1 (0.33) | — | |
| Methacrylic Acid SCHEMBL15443432 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL26179859 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106272-A1 | SMALL MOLECULE INHIBITORS OF APOBEC3G AND APOBEC3B | HARKI DANIEL A (US) | 2015-07-16 | — | — | WO | disclosed |