Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15293403 | 0.83 | CRBN (0.41) | CRBNALDH1A1TAS2R38 | |
| SCHEMBL25711985 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL14930766 | 0.80 | RAB9A (0.34) | CRBNTAS2R38 | |
| SCHEMBL14566054 | 0.79 | MGAM (0.32) | ALDH1A1 | |
| SCHEMBL24567199 | 0.77 | — | — | |
| SCHEMBL18551018 | 0.76 | — | — | |
| SCHEMBL18950864 | 0.76 | CRBN (0.32) | CRBNALDH1A1TAS2R38 | |
| SCHEMBL5671901 | 0.75 | — | — | |
| SCHEMBL18790800 | 0.74 | TAS2R38 (0.33) | CRBNTAS2R38 | |
| SCHEMBL16907910 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |