SCHEMBL1691506

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1691661	0.85	KDM4E (0.69)	KDM4EKCNK3KCNK9NPC1POLB
	SCHEMBL1691474	0.85	ALDH1A1 (0.58)	ALDH1A1KDM4EKCNK3KCNK9NPC1
	Hydrochloric Acid SCHEMBL1430012	0.84	ALDH1A1 (0.57)	ALDH1A1KDM4EHPGDKCNK3KCNK9
	SCHEMBL2198214	0.82	ALDH1A1 (0.54)	ALDH1A1KDM4EHPGDKCNK3KCNK9
	SCHEMBL18963128	0.82	KDM4E (0.57)	KDM4EKCNK3KCNK9NPC1POLB
	SCHEMBL1691664	0.80	PTGS2 (0.54)	KDM4ENPC1POLBHTTRAB9A
	SCHEMBL13341899	0.79	NPC1 (0.55)	ALDH1A1KDM4EHPGDNPC1POLB
	SCHEMBL1431645	0.78	KCNK3 (0.50)	ALDH1A1KDM4EHPGDKCNK3KCNK9
	SCHEMBL7894902	0.77	AKT1 (0.40)	ALDH1A1KDM4EHPGDKCNK3KCNK9
	SCHEMBL1691303	0.77	GABRA1 (0.68)	ALDH1A1KDM4EHPGDPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.