Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrabactin A SCHEMBL2476266 | 0.86 | ALDH1A1 (0.50) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4489640 | 0.85 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4443025 | 0.85 | NSD2 (0.65) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4446948 | 0.84 | NSD2 (0.66) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27807434 | 0.84 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1831060 | 0.81 | SLC1A3 (0.47) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| Pyrabactin A SCHEMBL29395044 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| Pyrabactin A SCHEMBL9932519 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| Pyrabactin A SCHEMBL30157573 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28967790 | 0.80 | TSHR (0.51) | MEN1KMT2AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106455565-A | Use of substituted oxotetrahydroquinoline sulfonamides or salts thereof for increasing stress tolerance in plants | 拜耳作物科学股份公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2658375-A2 | USE OF OPEN-CHAIN CARBOXYLIC ACIDS, CARBONIC ESTERS, CARBOXAMIDES AND CARBONITRILES OF ARYL, HETEROARYL AND BENZYLSULFONAMIDE OR THE SALTS THEREOF FOR IMPROVING THE STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2658376-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2611300-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | Bayer Intellectual Property GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2547204-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | Bayer Intellectual Property GmbH (DE) | 2013-01-23 | — | — | EP | disclosed |
| WO-2012089721-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012089722-A2 | USE OF OPEN-CHAIN CARBOXYLIC ACIDS, CARBONIC ESTERS, CARBOXAMIDES AND CARBONITRILES OF ARYL, HETEROARYL AND BENZYLSULFONAMIDE OR THE SALTS THEREOF FOR IMPROVING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2011113861-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | WO | disclosed |