Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169187 | 0.81 | L3MBTL1 (0.60) | L3MBTL1KDM4EALDH1A1HSD17B10HPGD | |
| Pyrabactin A SCHEMBL2476266 | 0.72 | ALDH1A1 (0.50) | L3MBTL1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL12658168 | 0.71 | F2 (0.54) | SMN1; SMN2KDM4EALDH1A1MAPTF2 | |
| SCHEMBL1833222 | 0.71 | F2 (0.54) | SMN1; SMN2KDM4EALDH1A1MAPTF2 | |
| SCHEMBL1833219 | 0.71 | F2 (0.54) | SMN1; SMN2KDM4EALDH1A1MAPTF2 | |
| SCHEMBL6006417 | 0.70 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1KDM4EALDH1A1 | |
| SCHEMBL4443025 | 0.70 | NSD2 (0.65) | L3MBTL1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9468163 | 0.70 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4446948 | 0.69 | NSD2 (0.66) | L3MBTL1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7768609 | 0.68 | KDM4E (0.67) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320520-B1 | SULFONYLGUANIDINE | GRUENENTHAL GMBH (DE) | 2011-05-11 | — | — | EP | claimed |