SCHEMBL16919867

SCHEMBL16919867

Cc1cccc2c1sc1nccnc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.42
HTR1A P08908 1/20 0.40
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40
PSMD14 O00487 2/20 0.40
COPS5 Q92905 2/20 0.40
NPC1 O15118 1/20 0.38
HSP90AA1 P07900 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CLK1 P49759 2/20 0.38
CDC7 O00311 1/20 0.38
DBF4 Q9UBU7 1/20 0.38
CYP2A6 P11509 2/20 0.37
CYP1A2 P05177 1/20 0.37
CCR1 P32246 2/20 0.36
CCR8 P51685 2/20 0.36
SLC6A2 P23975 1/20 0.36
HTT P42858 1/20 0.36
CCR5 P51681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19039387 0.80 PSMD14 (0.49) LIMK1HTR1AADRA1DADRA1AADRA1B
SCHEMBL16283920 0.80 LIMK1 (0.50) LIMK1PSMD14COPS5NPC1HSP90AA1
SCHEMBL16283921 0.77 L3MBTL1 (0.46) LIMK1HTR1AADRA1DADRA1AADRA1B
SCHEMBL20042620 0.74 CYP1A1 (0.40) LIMK1NPC1HSP90AA1L3MBTL1CLK1
SCHEMBL9851983 0.74 CYP2A6 (0.35) LIMK1L3MBTL1CYP2A6CYP1A2ELANE
SCHEMBL16919875 0.74 CLK1 (0.55) LIMK1PSMD14COPS5NPC1HSP90AA1
SCHEMBL29364650 0.71 CYP1A2 (0.55) L3MBTL1CYP2A6CYP1A2ALDH1A1
SCHEMBL142551 0.71 CYP1A2 (0.55) L3MBTL1CYP2A6CYP1A2ALDH1A1
SCHEMBL24623623 0.71 LIMK1 (0.51) LIMK1PSMD14COPS5NPC1HSP90AA1
SCHEMBL19039386 0.70 LIMK1 (0.43) LIMK1NPC1CLK1CDC7DBF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2910555-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2019-03-27 EP disclosed
US-9755159-B2 Organic materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2017-09-05 US disclosed
US-9755159-B2 Organic materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2017-09-05 US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS OCIAD1, OCIAD2, SLC25A21 LIMK1 4180/4885HTR1A 2563/4885ADRA1D 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.