Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 3/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903332 | 0.84 | LIMK1 (0.50) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL11884995 | 0.81 | LIMK1 (0.50) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL24623997 | 0.79 | CLK1 (0.53) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL24624030 | 0.79 | CLK1 (0.49) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL15374732 | 0.77 | GPR3 (0.46) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL26423662 | 0.76 | LIMK1 (0.46) | LIMK1CLK1CDC7DBF4NPC1 | |
| SCHEMBL24624032 | 0.75 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL17051494 | 0.74 | LIMK1 (0.49) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL16919875 | 0.74 | CLK1 (0.55) | LIMK1CLK1CDC7DBF4HSP90AA1 | |
| SCHEMBL26423698 | 0.74 | LIMK1 (0.44) | LIMK1CLK1CDC7DBF4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | NR0B2, FPR3, NPR3 | LIMK1 3355/4885CLK1 2296/4885CDC7 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.