SCHEMBL16922650

SCHEMBL16922650

Cc1ccc(N(c2ccccc2)c2ccc(/C=C/c3ccc(N(c4ccc(C)cc4)c4ccc(/C=C/c5ccc(N(c6ccccc6)c6ccc(C(F)(F)F)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.54
CYP1A1 P04798 2/20 0.49
CYP1B1 Q16678 2/20 0.49
TRPM8 Q7Z2W7 2/20 0.44
RELA Q04206 1/20 0.43
AHR P35869 1/20 0.42
PTGS1 P23219 1/20 0.42
NR1H3 Q13133 1/20 0.42
NQO2 P16083 1/20 0.41
MAOB P27338 1/20 0.41
APP P05067 1/20 0.41
ERBB2 P04626 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16926002 1.00 NFE2L2 (0.54) NFE2L2CYP1A1CYP1B1TRPM8RELA
SCHEMBL14027834 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL2605486 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL14199696 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL5494966 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL16790468 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL14003818 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL10082096 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL12763707 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1
SCHEMBL10092966 0.87 RELA (0.55) NFE2L2CYP1B1TRPM8RELAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9507284-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, image-forming apparatus, and triarylamine compound MITSUBISHI CHEMICAL CORPORATION (JP) 2016-11-29 US disclosed
US-20150205217-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, IMAGE-FORMING APPARATUS, AND TRIARYLAMINE COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150205217-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, IMAGE-FORMING APPARATUS, AND TRIARYLAMINE COMPOUND ALDH1A2, SLC18A2, SLC1A2 NFE2L2 522/4885CYP1A1 2010/4885CYP1B1 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.