Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 12/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740984 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL7271706 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL16935203 | 0.72 | ALDH1A1 (0.96) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL24256907 | 0.71 | ALDH1A1 (0.94) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL9846227 | 0.70 | ALDH1A1 (0.93) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL15923482 | 0.70 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL16935255 | 0.68 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL14499342 | 0.67 | POLB (0.76) | ALDH1A1KDM4EHPGDKMT2ACYP1A2 | |
| SCHEMBL16935340 | 0.67 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 | |
| SCHEMBL16935353 | 0.65 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDKMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015110999-A1 | EZH2 INHIBITORS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-07-30 | — | — | WO | disclosed |