Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20596500 | 0.96 | KDM4E (0.49) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL18676929 | 0.92 | KDM4E (0.38) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL29997093 | 0.91 | KMT2A (0.44) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL29995754 | 0.91 | KDM4E (0.41) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL29996605 | 0.91 | KDM4E (0.41) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL20252100 | 0.90 | L3MBTL1 (0.43) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL20596516 | 0.90 | KDM4E (0.47) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL22058282 | 0.90 | KDM4E (0.47) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL29996529 | 0.90 | PTGER4 (0.40) | KDM4EL3MBTL1ATMKMT2APTGER4 | |
| SCHEMBL29996436 | 0.90 | L3MBTL1 (0.49) | KDM4EL3MBTL1ATMKMT2AIL1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210217966-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-07-15 | — | — | US | disclosed |
| US-10991892-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-04-27 | — | — | US | disclosed |
| EP-2875019-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-20150214489-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20150214489-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150214489-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MT-CO3, MT-ND3, MT-ND5 | KDM4E 2392/4885L3MBTL1 2040/4885ATM 2816/4885 |
| US-20210217966-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MT-CO3, MT-ND3, MT-ND5 | KDM4E 2392/4885L3MBTL1 2040/4885ATM 2816/4885 |
| US-10991892-B2 | Materials for organic electroluminescent devices | MT-CO3, MT-ND3, MT-ND5 | KDM4E 2392/4885L3MBTL1 2040/4885ATM 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.