SCHEMBL169447

SCHEMBL169447

OCCCCCc1ncncn1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
TBXAS1 P24557 2/20 0.35
TLR7 Q9NYK1 2/20 0.33
NAAA Q02083 1/20 0.32
CA2 P00918 1/20 0.32
LOX P28300 1/20 0.32
AOC3 Q16853 1/20 0.32
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29180589 0.98 KDM4E (0.37) KDM4ETBXAS1TLR7CA2LOX
SCHEMBL2747913 0.91 HSP90AA1 (0.32) KDM4E
SCHEMBL467539 0.80
SCHEMBL29263650 0.79 NAAA (0.50) KDM4ETBXAS1TLR7NAAACA2
SCHEMBL9741621 0.79 NAAA (0.50) KDM4ETBXAS1TLR7NAAACA2
SCHEMBL28036517 0.78
SCHEMBL2708603 0.77 KCNH2 (0.42) KDM4ETBXAS1LMNAMAPTKMT2A
SCHEMBL6017591 0.77 HRH1 (0.47)
SCHEMBL11265989 0.77 KCNH2 (0.42) KDM4ETBXAS1LMNAMAPTKMT2A
SCHEMBL7036037 0.76 NAAA (0.47) KDM4ETBXAS1TLR7NAAACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078698-B1 POLYARYLENE POLYMERS ROHM & HAAS ELECT MAT (US) 2019-11-20 EP claimed
EP-3078698-A1 POLYARYLENE POLYMERS Rohm and Haas Electronic Materials LLC (US) 2016-10-12 EP claimed
US-20160289493-A1 POLYARYLENE POLYMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-10-06 US claimed
US-8383088-B2 Coumestan-like antioxidants and UV absorbants BASF SE (DE) 2013-02-26 US claimed
EP-2121141-B1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS BASF SE (DE) 2012-02-15 EP claimed
US-20100330009-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS CIBA CORPORATION (US) 2010-12-30 US claimed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US claimed
EP-2121141-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS BASF SE (DE) 2009-11-25 EP claimed
US-20090143506-A1 Aldehyde inhibitor composition and polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-06-04 US claimed
WO-2008110465-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS BASF SE (CH) 2008-09-18 WO claimed
EP-0697481-A2 Aqueous textile treatment compositions containing an ultra-violet absorbing agent CIBA-GEIGY AG (CH) 1996-02-21 EP claimed
EP-0682145-A2 Textile treatment CIBA-GEIGY AG (CH) 1995-11-15 EP claimed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 US claimed
EP-0659877-A2 Composition for the treatment of textiles CIBA-GEIGY AG (CH) 1995-06-28 EP claimed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 EP claimed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP claimed
US-5208012-A Phenolic triazine DAIKYO GOMU SEIKO LTD. (JP) 1993-05-04 US claimed
EP-0525262-A1 Anti-inflammatory cosmetic composition DAIKYO GOMU SEIKO LTD. (JP) 1993-02-03 EP claimed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100330009-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS TYR, NQO1, SIRT3 KDM4E 1307/4885TBXAS1 1125/4885TLR7 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.