SCHEMBL6017591

SCHEMBL6017591

NCCCCCc1ncncn1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 12/20 0.47
HRH3 Q9Y5N1 4/20 0.42
HRH4 Q9H3N8 3/20 0.42
HRH2 P25021 2/20 0.42
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6118291 0.91 HRH3 (0.39) HRH1HRH3HRH4HRH2
SCHEMBL1661905 0.80
SCHEMBL29263696 0.79 HRH1 (0.59) HRH1HRH3HRH4HRH2MAOA
SCHEMBL6685773 0.79 HRH1 (0.59) HRH1HRH3HRH4HRH2MAOA
SCHEMBL28091635 0.77 KCNH2 (0.42)
SCHEMBL20499801 0.77 KCNH2 (0.42)
SCHEMBL2708603 0.77 KCNH2 (0.42)
SCHEMBL20747030 0.77 KCNH2 (0.42)
SCHEMBL169447 0.77 KDM4E (0.36)
SCHEMBL27794520 0.77 KCNH2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060252857-A1 Aminoaryl-1-3-5-triazines and their use as uv absorbers SCHAEFER THOMAS 2006-11-09 US disclosed
CN-1795182-A Aminoaryl-1, 3, 5-triazines and their use as UV absorbers CIBA SC HOLDING AG (CH) 2006-06-28 CN disclosed
EP-1641768-A2 AMINOARYL-1-3-5 TRIAZINES AND THEIR USE AS UV ABSORBERS Ciba SC Holding AG (CH) 2006-04-05 EP disclosed
WO-2004106311-A2 AMINOARYL-1-3-5 TRIAZINES AND THEIR USE AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252857-A1 Aminoaryl-1-3-5-triazines and their use as uv absorbers IK, CRY2, CRY1 HRH1 118/4885HRH3 180/4885HRH4 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.