Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.68 |
| ▸ | PRKACA | P17612 | 2/20 | 0.67 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | SRC | P12931 | 2/20 | 0.66 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.66 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.66 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14178285 | 1.00 | PLA2G2A (0.68) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| SCHEMBL2790606 | 1.00 | PLA2G2A (0.68) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| SCHEMBL15297005 | 1.00 | PLA2G2A (0.68) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| Adenosine SCHEMBL8577634 | 0.96 | ADORA3 (0.71) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| SCHEMBL3429291 | 0.94 | PLA2G2A (0.69) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| SCHEMBL16945766 | 0.94 | PLA2G2A (0.69) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| Adenosine SCHEMBL15538483 | 0.92 | ADORA1 (0.65) | PLA2G2APRKACAP2RY1ADORA1P2RY2 | |
| SCHEMBL1066705 | 0.91 | PRKACA (0.66) | PRKACAP2RY1ADORA1P2RY2SMN1; SMN2 | |
| SCHEMBL13869231 | 0.91 | PRKACA (0.69) | PRKACAP2RY1ADORA1P2RY2SMN1; SMN2 | |
| SCHEMBL15538484 | 0.91 | PRKACA (0.66) | PRKACAP2RY1ADORA1P2RY2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657246-B1 | MODULATOR OF ACTIVITY OF ADENYLATE CYCLASE | PUBLIC UNIV CORP YOKOHAMA CITY (JP) | 2016-04-13 | — | — | EP | claimed |
| US-9096632-B2 | Modulator of activity of adenylate cyclase | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-08-04 | — | — | US | claimed |
| EP-2657246-B1 | MODULATOR OF ACTIVITY OF ADENYLATE CYCLASE | PUBLIC UNIV CORP YOKOHAMA CITY (JP) | 2016-04-13 | — | — | EP | disclosed |