SCHEMBL2790606

SCHEMBL2790606

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COC(=O)CCC(=O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.68
PRKACA P17612 2/20 0.67
P2RY1 P47900 4/20 0.66
ADORA1 P30542 3/20 0.66
P2RY2 P41231 3/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
SRC P12931 2/20 0.66
DNPH1 O43598 1/20 0.66
PRKAB2 O43741 1/20 0.66
TRPM2 O94759 1/20 0.66
LDHA P00338 1/20 0.66
ADRB2 P07550 1/20 0.66
FBP1 P09467 1/20 0.66
PRKAG1 P54619 1/20 0.66
PRKAA2 P54646 1/20 0.66
PDE4D Q08499 1/20 0.66
KCNH2 Q12809 1/20 0.66
PRKAA1 Q13131 1/20 0.66
PDE3A Q14432 1/20 0.66
TAS1R3 Q7RTX0 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16945765 1.00 PLA2G2A (0.68) PLA2G2APRKACAP2RY1ADORA1P2RY2
SCHEMBL14178285 1.00 PLA2G2A (0.68) PLA2G2APRKACAP2RY1ADORA1P2RY2
SCHEMBL15297005 1.00 PLA2G2A (0.68) PLA2G2APRKACAP2RY1ADORA1P2RY2
Adenosine SCHEMBL8577634 0.96 ADORA3 (0.71) PLA2G2APRKACAP2RY1ADORA1P2RY2
SCHEMBL3429291 0.94 PLA2G2A (0.69) PLA2G2APRKACAP2RY1ADORA1P2RY2
SCHEMBL16945766 0.94 PLA2G2A (0.69) PLA2G2APRKACAP2RY1ADORA1P2RY2
Adenosine SCHEMBL15538483 0.92 ADORA1 (0.65) PLA2G2APRKACAP2RY1ADORA1P2RY2
SCHEMBL1066705 0.91 PRKACA (0.66) PRKACAP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL13869231 0.91 PRKACA (0.69) PRKACAP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL15538484 0.91 PRKACA (0.66) PRKACAP2RY1ADORA1P2RY2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117802180-A Genetic engineering bacterium for producing xanthine and construction method and application thereof 新疆瑞诺生物科技有限公司 2024-04-02 CN claimed
CN-114317386-B Genetic engineering strain for producing inosine and construction method and application thereof 天津科技大学 2023-12-08 CN claimed
US-9764168-B2 Taste masking compositions and edible forms thereof ACME SPECIALTY PRODUCTS, LLC (US) 2017-09-19 US claimed
US-9668505-B2 Taste masking compositions and edible forms thereof for masking the taste of foods ACME SPECIALTY PRODUCTS, LLC (US) 2017-06-06 US claimed
WO-2010116385-A2 PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING UNPLEASANT TASTE RUBICON RESEARCH PRIVATE LIMITED (IN) 2010-10-14 WO claimed
US-7777023-B2 Method for the chemical synthesis of oligonucleotides SIRNA THERAPEUTICS, INC. (US) 2010-08-17 US claimed
EP-1139793-B1 INHIBITORS OF THE BITTER TASTE RESPONSE SINAI SCHOOL MEDICINE (US) 2009-10-14 EP claimed
US-RE40594-E1 Inhibitors of the bitter taste response MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) 2008-12-02 US claimed
EP-1928267-A1 METHODS AND COMPOSITIONS TO IMPROVE THE PALATABILITY OF FOODS MCNEIL NUTRITIONALS LLC (US) 2008-06-11 EP claimed
WO-2007033064-A1 METHODS AND COMPOSITIONS TO IMPROVE THE PALATABILITY OF FOODS MCNEIL NUTRITIONALS, LLC (US) 2007-03-22 WO claimed
US-20070059421-A1 Methods and compositions to improve the palatability of foods MCNEIL NUTRITIONALS, LLC 2007-03-15 US claimed
US-6995259-B1 Method for the chemical synthesis of oligonucleotides SIRNA THERAPEUTICS, INC. (US) 2006-02-07 US claimed
US-6540978-B1 Method of identifying, by contacting a taste receptor with a G-protein selected from transducin and gustducin, and a bitter tastant; the inhibitors include adenosine 5'-diphosphate, and 5'-cytidylic acid MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY 2003-04-01 US claimed
CN-119199132-A Novel protein marker for judging muscle injury degree as well as acquisition method and application thereof 河北医科大学第三医院 2024-12-27 CN disclosed
CN-119044349-A Metabolism physiological age prediction and aging assessment method 哈尔滨脉图精准技术有限公司 2024-11-29 CN disclosed
CN-118360171-A Recombinant cordyceps militaris for improving cordycepin yield and application 浙江工业大学 2024-07-19 CN disclosed
WO-2000038536-A2 INHIBITORS OF THE BITTER TASTE RESPONSE MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) 2000-07-06 WO disclosed
US-5773424-A PARASITICIDE RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-06-30 US disclosed
EP-0755255-A1 TREATMENT OF TOXOPLASMOSIS UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) 1997-01-29 EP disclosed
WO-1996018398-A1 TREATMENT OF TOXOPLASMOSIS THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) 1996-06-20 WO disclosed