Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355295 | 0.89 | RAB9A (0.58) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL15096391 | 0.88 | HPGD (0.47) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL15096399 | 0.87 | AKR1C3 (0.50) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL17208771 | 0.82 | CA9 (0.58) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL13437570 | 0.82 | MAOB (0.53) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL17208777 | 0.80 | CA12 (0.45) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL15541679 | 0.80 | GLA (0.57) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL18469631 | 0.80 | MAOB (0.45) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL23350788 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL16934840 | 0.77 | RXFP1 (0.57) | ALDH1A1HPGDKDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925951-A1 | PROCESS FOR THE CYCLOADDITION OF A(HETERO)ARYL 1,3-DIPOLE COMPOUND WITH A (HETERO)CYCLOALKYNE | SynAffix B.V. (NL) | 2021-12-22 | — | — | EP | disclosed |
| US-11168085-B2 | Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne | SYNAFFIX B.V. (NL) | 2021-11-09 | — | — | US | disclosed |
| EP-3097079-B1 | PROCESS FOR THE CYCLOADDITION OF A HETERO(ARYL) 1,3-DIPOLE COMPOUND WITH A (HETERO)CYCLOALKYNE | SYNAFFIX BV (NL) | 2021-05-12 | — | — | EP | disclosed |
| US-20170002012-A1 | PROCESS FOR THE CYCLOADDITION OF A HETERO(ARYL) 1,3-DIPOLE COMPOUND WITH A (HETERO)CYCLOALKYNE | SYNAFFIX B.V. (NL) | 2017-01-05 | — | — | US | disclosed |
| WO-2015112014-A1 | PROCESS FOR THE CYCLOADDITION OF A HETERO(ARYL) 1,3-DIPOLE COMPOUND WITH A (HETERO)CYCLOALKYNE | STICHTING KATHOLIEKE UNIVERSITEIT (NL) | 2015-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002012-A1 | PROCESS FOR THE CYCLOADDITION OF A HETERO(ARYL) 1,3-DIPOLE COMPOUND WITH A (HETERO)CYCLOALKYNE | AHR, CYP1B1, NAT1 | ALDH1A1 362/4885HPGD 894/4885KDM4E 3653/4885 |
| US-11168085-B2 | Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne | AHR, CYP1B1, NAT1 | ALDH1A1 362/4885HPGD 894/4885KDM4E 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.