Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948154 | 0.88 | ALDH1A1 (0.50) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL18355295 | 0.86 | RAB9A (0.58) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL15096399 | 0.85 | AKR1C3 (0.50) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL17208771 | 0.80 | CA9 (0.58) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7030488 | 0.78 | HPGD (0.51) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL15541679 | 0.78 | GLA (0.57) | HPGDKDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL17208777 | 0.78 | CA12 (0.45) | HPGDKDM4EALDH1A1MAPTGLA | |
| SCHEMBL18469631 | 0.77 | MAOB (0.45) | HPGDKDM4EALDH1A1MAPTGLA | |
| SCHEMBL13437570 | 0.77 | MAOB (0.53) | HPGDKDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL16934840 | 0.75 | RXFP1 (0.57) | HPGDKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130178609-A1 | MODULAR CONSTRUCTION OF LIPOPHOSPHOLIPIDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2013-07-11 | — | — | US | disclosed |
| US-20130178609-A1 | MODULAR CONSTRUCTION OF LIPOPHOSPHOLIPIDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178609-A1 | MODULAR CONSTRUCTION OF LIPOPHOSPHOLIPIDS | SGMS2, SGMS1, DEGS1 | HPGD 3858/4885KDM4E 4216/4885ALDH1A1 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.