Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292209 | 0.73 | CYP1A2 (0.41) | CYP1A2CYP2A6TACR1MEN1KMT2A | |
| SCHEMBL3800271 | 0.73 | GAA (0.56) | CYP1A2CYP2A6GAANPC1MEN1 | |
| SCHEMBL2385413 | 0.71 | CYP4F2 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL7639928 | 0.71 | GAA (0.50) | CYP1A2CYP2A6GAAKDM4EMEN1 | |
| SCHEMBL8469059 | 0.71 | PPARG (0.56) | CYP1A2CYP2A6GAATACR1ALDH1A1 | |
| SCHEMBL28270204 | 0.70 | CYP1A2 (0.63) | CYP1A2CYP2A6GAAKDM4ENPC1 | |
| SCHEMBL8081828 | 0.70 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL23257472 | 0.70 | HTR2A (0.53) | CYP1A2CYP2A6GAATACR1 | |
| SCHEMBL20521930 | 0.70 | CYP1A2 (0.47) | CYP1A2CYP2A6GAATACR1KDM4E | |
| SCHEMBL27787124 | 0.70 | GAA (0.52) | CYP1A2CYP2A6GAATACR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4138923-A1 | DRUG ANTIBODY CONJUGATES | Pharma Mar, S.A. (ES) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214126-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2021-10-28 | — | — | WO | disclosed |
| EP-2825542-A1 | LIVER X RECEPTOR MODULATORS | Vitae Pharmaceuticals, Inc. (US) | 2015-01-21 | — | — | EP | disclosed |
| WO-2013138568-A1 | LIVER X RECEPTION MODULATORS | VITAE PHARMACEUTICALS, INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| EP-2576569-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF ECTEINASCIDIN COMPOUNDS | Pharma Mar S.A. (ES) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011147828-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF ECTEINASCIDIN COMPOUNDS | PHARMA MAR, S.A. (ES) | 2011-12-01 | — | — | WO | disclosed |