Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639432 | 0.87 | MMP8 (0.56) | CYP1A2CYP2A6GAAALDH1A1RECQL | |
| SCHEMBL12802204 | 0.87 | CYP1A2 (0.46) | CYP1A2CYP2A6GAAALDH1A1RECQL | |
| SCHEMBL16595186 | 0.85 | CYP1A2 (0.45) | CYP1A2CYP2A6GAAALDH1A1RECQL | |
| SCHEMBL1221957 | 0.84 | MMP8 (0.44) | CYP1A2CYP2A6GAAALDH1A1RECQL | |
| SCHEMBL6570404 | 0.81 | GAA (0.46) | CYP1A2CYP2A6GAAALDH1A1RECQL | |
| SCHEMBL4419400 | 0.80 | ALDH1A1 (0.62) | ALDH1A1RECQLMMP8PIN1LMNA | |
| SCHEMBL16595190 | 0.77 | SLC13A5 (0.48) | CYP1A2CYP2A6GAAPPARGPPARA | |
| SCHEMBL8872531 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2A6 | |
| SCHEMBL3800271 | 0.76 | GAA (0.56) | CYP1A2CYP2A6GAAALDH1A1MEN1 | |
| SCHEMBL13721608 | 0.76 | MMP8 (0.47) | CYP1A2ALDH1A1RECQLMMP8PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601234-A1 | BARBITURIC ACID DERIVATIVES COMPRISING CATIONIC AND LIPOPHILIC GROUPS | Universitetet i Tromsø - Norges Arktiske Universitet (NO) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018178198-A1 | BARBITURIC ACID DERIVATIVES COMPRISING CATIONIC AND LIPOPHILIC GROUPS | UNIVERSITETET I TROMSØ - NORGES ARKTISKE UNIVERSITET (NO) | 2018-10-04 | — | — | WO | disclosed |