SCHEMBL169502

SCHEMBL169502

C=C(C)C(=O)OCC=CN

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1235588 0.98 TSHR (0.44) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL1636583 0.87 TSHR (0.52) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL1636584 0.87 TSHR (0.52) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL5654625 0.87 TSHR (0.52) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL10606524 0.81 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL7521766 0.81 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL453100 0.81 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL37916 0.81 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL16767717 0.80 TSHR (0.42) TSHRTHRBALDH1A1TDP1POLB
Ethylene SCHEMBL8679128 0.79 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5222 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112040936-B Transdermal therapeutic system for transdermal administration of solifenacin 罗曼治疗系统股份公司 2024-07-23 CN claimed
US-20240189313-A1 SOLID DISPERSIONS InventisBio Co., Ltd. (CN) 2024-06-13 US claimed
US-11963951-B2 Pharmaceutical compositions XSPRAY PHARMA AB (SE) 2024-04-23 US claimed
CN-114599349-B Transdermal therapeutic system for transdermal administration of fingolimod 罗曼治疗系统股份公司 2024-04-09 CN claimed
WO-2024058093-A1 TIMED-RELEASE GRANULES AND USE THEREOF 東和薬品株式会社 2024-03-21 WO claimed
CN-113769059-B Poly (zinc prasugrel) granule and preparation method thereof 北京鑫开元医药科技有限公司 2024-02-13 CN claimed
CN-114126590-B Pharmaceutical preparation and method for producing the same 富士制药工业股份有限公司 2024-01-05 CN claimed
CN-115518052-B Gastric retention preparation and preparation method thereof 江苏集萃新型药物制剂技术研究所有限公司 2024-01-02 CN claimed
WO-2023247435-A1 BILAYER TABLETS OF VALSARTAN AND INDAPAMIDE KRKA, D.D., NOVO MESTO (SI) 2023-12-28 WO claimed
WO-2023249087-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING SAME 三生医薬株式会社 2023-12-28 WO claimed
US-4295909-A ADHESIVE AND SEALANT, URETHANE-ACRYLATE-CAPPED POLYOL OR POLYAMINE OF POLYBUTADIENE OR BUTADIENE COPOLYMER LOCTITE CORPORATION (US) 1981-10-20 US claimed
EP-0006777-B1 A PROCESS FOR PREPARING POLYMERS USABLE AS FLOCCULANTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-10-14 EP claimed
US-4294676-A Aqueous monomer solutions adapted for direct photopolymerization RHONE-POULENC INDUSTRIES (FR) 1981-10-13 US claimed
US-4293635-A N-ALKYLACRYLAMIDE-UNSATURATED ACID-ACRYLATE INTERPOLYMER, AMPHOTERIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-06 US claimed
US-4252625-A IN A MOIST, HUMID ENCLOSED ENVIRONMENT RHONE-POULENC INDUSTRIES (FR) 1981-02-24 US claimed
US-4178221-A Process for the preparation of water-soluble acrylic polymers by photopolymerization RHONE-POULENC INDUSTRIES (FR) 1979-12-11 US claimed
US-4133942-A Polymeric carrier for a controlled synthesis of peptides and the method of its preparation CESKOSLOVENSKA AKADEMIE VED (CS) 1979-01-09 US claimed
US-4111859-A METHOD OF PREPARATION OF ION EXCHANGERS BY ALKYLATION AND HYDROXYALKYLATION OF POLYMERIC HYDROPHILIC ANION EXCHANGERS CESKOSLOVENSKA AKADEMIE VED (CS) 1978-09-05 US claimed
US-4097420-A Method for preparation of macroporous amphoteric ion exchangers with highly crosslinked hydrophilic polymeric matrix CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US claimed
US-4018851-A Curable poly(alkylene) ether polyol-based grafted resins having improved properties LOCTITE CORPORATION (US) 1977-04-19 US claimed