Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956096 | 0.85 | GABRA1 (0.45) | MAP3K14HTR2CSLC6A2FAAHCA1 | |
| SCHEMBL16951488 | 0.83 | GABRA1 (0.39) | HTR2CSLC6A2FAAHCA1CA2 | |
| SCHEMBL16962184 | 0.82 | MAP3K14 (0.33) | MAP3K14HTR2CALDH1A1 | |
| SCHEMBL16950597 | 0.81 | ADRA2A (0.36) | HTR2C | |
| SCHEMBL16954875 | 0.80 | CYP1A2 (0.39) | HTR2CLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL16953574 | 0.80 | — | — | |
| SCHEMBL16956724 | 0.80 | GABRA1 (0.39) | HTR2CSLC6A2FAAHCA1CA2 | |
| SCHEMBL16956819 | 0.80 | ABCB1 (0.41) | HTR2CSLC6A2CYP3A4HTR2BALDH1A1 | |
| SCHEMBL16955804 | 0.80 | IDO1 (0.32) | — | |
| SCHEMBL16955516 | 0.80 | MAP3K14 (0.35) | MAP3K14CYP1A2CYP3A4GABRA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |