Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957899 | 0.82 | CHRNB2 (0.33) | — | |
| SCHEMBL16960511 | 0.81 | GABRA1 (0.35) | GABRA1 | |
| SCHEMBL16954797 | 0.81 | ABCB1 (0.39) | OPRM1OPRL1 | |
| SCHEMBL16954916 | 0.81 | SLC18A3 (0.33) | — | |
| SCHEMBL16957269 | 0.81 | — | — | |
| SCHEMBL16960204 | 0.81 | OPRL1 (0.36) | ALDH1A1KMT2AOPRM1OPRL1 | |
| SCHEMBL16958362 | 0.80 | ABCB1 (0.43) | CYP1A2CYP2C19 | |
| SCHEMBL16954220 | 0.80 | MAPT (0.36) | ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL16950667 | 0.80 | MAP3K14 (0.35) | MAP3K14ALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL16955049 | 0.79 | ADRA2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |