Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953435 | 0.89 | TRPV4 (0.49) | TRPV4ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL16950789 | 0.80 | HPGD (0.50) | ALDH1A1GAAKDM4EMEN1USP2 | |
| SCHEMBL16955918 | 0.80 | AR (0.46) | ALDH1A1KDM4EMEN1USP2KMT2A | |
| SCHEMBL16952112 | 0.78 | IRAK4 (0.38) | TRPV4SLC6A9ALKAR | |
| SCHEMBL16952284 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EMEN1USP2 | |
| SCHEMBL16955606 | 0.77 | NQO1 (0.41) | ALDH1A1GAAKDM4EMEN1USP2 | |
| SCHEMBL16959816 | 0.77 | MAPT (0.46) | ALDH1A1GAAKDM4EMEN1USP2 | |
| SCHEMBL16952407 | 0.77 | HTR2A (0.44) | ALDH1A1GAAKDM4EMEN1USP2 | |
| SCHEMBL11890400 | 0.76 | TRPV4 (0.51) | TRPV4ALDH1A1GAAMEN1USP2 | |
| SCHEMBL16198782 | 0.76 | ALDH1A1 (0.51) | TRPV4ALDH1A1GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |