Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961368 | 0.88 | TSHR (0.47) | HPGDCYSLTR2CYSLTR1SMN1; SMN2NPC1 | |
| SCHEMBL16950830 | 0.83 | HPGD (0.47) | HPGDCYSLTR2CYSLTR1SMN1; SMN2KDM4E | |
| SCHEMBL16952284 | 0.82 | ALDH1A1 (0.46) | HPGDSMN1; SMN2KDM4ERAB9AALDH1A1 | |
| SCHEMBL16959816 | 0.81 | MAPT (0.46) | HPGDKDM4EALDH1A1HTTMAPT | |
| SCHEMBL16955606 | 0.81 | NQO1 (0.41) | CYSLTR2CYSLTR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL16952407 | 0.81 | HTR2A (0.44) | HPGDKDM4EALDH1A1HTTMAPT | |
| SCHEMBL16950719 | 0.80 | TRPV4 (0.40) | HPGDKDM4EALDH1A1HTTMAPT | |
| SCHEMBL16952981 | 0.79 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1HTTMEN1KMT2A | |
| SCHEMBL16956830 | 0.78 | LMNA (0.41) | HPGDSMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL16951779 | 0.77 | L3MBTL1 (0.42) | KDM4ELMNAALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |