Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953417 | 0.89 | TSHR (0.44) | HPGDCYSLTR2CYSLTR1SMN1; SMN2NPC1 | |
| SCHEMBL16957922 | 0.84 | HTR2C (0.42) | HPGDKDM4EALDH1A1HTTMAPT | |
| SCHEMBL16950789 | 0.83 | HPGD (0.50) | HPGDCYSLTR2CYSLTR1SMN1; SMN2KDM4E | |
| SCHEMBL16958642 | 0.82 | MAPT (0.43) | HPGDKDM4ETSHRALDH1A1HTT | |
| SCHEMBL16950337 | 0.81 | KDM4E (0.38) | SMN1; SMN2KDM4ENPC1LMNARAB9A | |
| SCHEMBL16961134 | 0.77 | CYP19A1 (0.48) | HPGDCYSLTR2CYSLTR1SMN1; SMN2NPC1 | |
| SCHEMBL16959761 | 0.77 | TDP1 (0.40) | HPGDSMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL16953614 | 0.77 | MCHR1 (0.35) | HPGDSMN1; SMN2KDM4ELMNATSHR | |
| SCHEMBL16961643 | 0.74 | HPGD (0.48) | HPGDCYSLTR2CYSLTR1SMN1; SMN2NPC1 | |
| SCHEMBL16962225 | 0.74 | EDNRB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |