Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950830 | 0.89 | HPGD (0.47) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16950337 | 0.85 | KDM4E (0.38) | TSHRALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL16961643 | 0.84 | HPGD (0.48) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16960641 | 0.82 | L3MBTL1 (0.39) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL16956882 | 0.82 | MAPT (0.41) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16961368 | 0.81 | TSHR (0.47) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16959581 | 0.81 | GAA (0.47) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16954699 | 0.80 | TRPV4 (0.46) | HPGDALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16954198 | 0.79 | HPGD (0.49) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16954881 | 0.77 | PYCR1 (0.33) | TSHRHPGDSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |